Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 31.21
Human Site: T572 Identified Species: 45.78
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 T572 Q K A M E L V T I N Y S S D L
Chimpanzee Pan troglodytes XP_001136622 741 82148 T572 Q K A M E L V T I N Y S S D L
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 T572 Q K A M E L V T I N Y S S D L
Dog Lupus familis XP_543150 987 105833 T818 Q K A M E L V T I N Y S S D L
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 M546 M R S V N D I M P M I G A R F
Rat Rattus norvegicus XP_002724835 883 95283 T714 Q K A M E L V T I N Y S S D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 Q566 I L Y L L T D Q N R L R S V N
Chicken Gallus gallus XP_417120 757 83269 T588 Q K A M E L V T I N Y S S D L
Frog Xenopus laevis NP_001128699 631 68072 N486 T M M S R H F N D P S A D A Y
Zebra Danio Brachydanio rerio XP_002666687 799 86684 S630 Q K A M E L V S I N Y S S D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 T622 Q S S I D M V T R N Y S T D L
Honey Bee Apis mellifera XP_623553 607 67474 V462 S N Q A R K S V T D L M P M I
Nematode Worm Caenorhab. elegans P34653 632 71182 N487 N S T R K T I N E I M P M I G
Sea Urchin Strong. purpuratus XP_796055 760 83393 A586 S A S V D L V A H Q Y S A D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 G534 K Y L I S D N G D S K K S I H
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 G511 K T V E T L L G G I T T H L A
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 0 100 N.A. 6.6 100 0 93.3 N.A. 53.3 0 0 40
P-Site Similarity: 100 100 100 100 N.A. 33.3 100 N.A. 13.3 100 6.6 100 N.A. 86.6 13.3 13.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 44 7 0 0 0 7 0 0 0 7 13 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 13 7 0 13 7 0 0 7 57 0 % D
% Glu: 0 0 0 7 44 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 13 7 0 0 7 0 0 7 % G
% His: 0 0 0 0 0 7 0 0 7 0 0 0 7 0 7 % H
% Ile: 7 0 0 13 0 0 13 0 44 13 7 0 0 13 7 % I
% Lys: 13 44 0 0 7 7 0 0 0 0 7 7 0 0 0 % K
% Leu: 0 7 7 7 7 57 7 0 0 0 13 0 0 7 57 % L
% Met: 7 7 7 44 0 7 0 7 0 7 7 7 7 7 0 % M
% Asn: 7 7 0 0 7 0 7 13 7 50 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 7 7 0 7 7 0 0 % P
% Gln: 50 0 7 0 0 0 0 7 0 7 0 0 0 0 0 % Q
% Arg: 0 7 0 7 13 0 0 0 7 7 0 7 0 7 0 % R
% Ser: 13 13 19 7 7 0 7 7 0 7 7 57 57 0 0 % S
% Thr: 7 7 7 0 7 13 0 44 7 0 7 7 7 0 0 % T
% Val: 0 0 7 13 0 0 57 7 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 0 0 0 0 0 0 57 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _